:root {
    --color-primary: #525CA3;
    --color-secondary: #7A00E6;
    --color-third: #8700F0;

    --color-text-btn: #23004C;

    --color-bg: #280059;
    --color-bg-25: #23004C;
    --color-bg-dark-25: #18003C;
    --color-bg-light-25: #300066;
    --color-white: #FFF;
    --color-black: #000;
    --font-sanofi: 'Inter', sans-serif;
}

body * {
    outline: none;
}
body {
    background: var(--color-bg);
}
header {
    padding: 30px;
}
.header {
    text-align: center;
    margin-bottom: 26px;
}
.three-items .image {
    position: relative;
    z-index: 1;
    display: flex;
    justify-content: center;
    align-items: center;
}
.three-items .image::before {
    content: "";
    position: absolute;
    top: calc(50% - 40px);
    left: calc(50% - 40px);
    background-color: #23004C;
    opacity: 1;
    border-radius: 50%;
    width: 80px;
    height: 80px;
    z-index: -1;
}
.header h1 {
    color: var(--color-white);
    font-size: 24px;
    line-height: 29px;
    font-weight: bold;
    margin-top: 30px;
}
.header h2 {
    color: var(--color-white);
    font-size: 16px;
    line-height: 19px;
    font-weight: 300;
    margin-top: 18px;
}
.header div {
    color: var(--color-third);
    font-size: 26px;
    line-height: 31px;
    font-weight: bold;
}
main {
    display: flex;
    flex-direction: row;
    justify-content: center;
    align-items: center;
    height: calc(100vh - 184px);
}
section {
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
}
a.btn.btn-primary,
button {
    margin: 30px 0;
    color: var(--color-text-btn);
    font-size: 18px;
    line-height: 22px;
    font-weight: bold;
    text-align: center;
    background-color: var(--color-white);
    padding: 19px 80px;
    border: 0;
    transition: 0.3s ease-in-out;
}
a.btn.btn-primary,
button.btn.btn-primary {

}

a.btn-secondary,
button.btn-secondary { 
    color: var(--color-white);
    font-size: 12px;
    line-height: 14px;
    font-weight: 500;
    text-align: center;
    background-color: transparent;
    padding: 14px 43px;
    border: 1px solid var(--color-secondary);
    text-decoration: none;
    border-radius: 50px;
    display: inline-block;
    transition: 0.3s ease-in-out;
}
a.btn-secondary:hover,
a.btn-secondary:active,
a.btn-secondary:focus,
button.btn-secondary:hover,
button.btn-secondary:active,
button.btn-secondary:focus { 
    background-color: var(--color-secondary);
    border: 1px solid var(--color-secondary);
    box-shadow: none;
}
.info {
    font-size: 16px;
}
.text-profile {
    color: #C6C7EF;
    font-size: 16px;
}
.text-left {
    text-align: left !important;
}
.info .title {
    color: var(--color-secondary);
    font-size: 16px;
    font-weight: bold;
}
.container {
    max-width: 620px;
    padding: 0;
 
}
.container.profile {
    max-width: 1000px;
}

.container .content {
    display: flex;
    flex-direction: column;
    background-color: var(--color-bg-25);
    padding: 25px 65px;
    border-radius: 8px;
    margin-bottom: 16px;
}
.container .content h2 {
    font-size: 16px;
    line-height: 22px;
    font-weight: 500;
    color: var(--color-white);
    text-align: center;
}
/* Range container */

.range-container {
    display: flex;
    flex-direction: row;
    justify-content: space-between;
    align-items: center;
    gap: 48px;
}
.range-container .scroll-bar {
    width: 100%;
}
.range-container .scroll-bar input {
    width: 100%;
}

.range-container input.custom-number {
    width: 55px;
    height: 40px;
    text-align: center;
    background-color: var(--color-bg-dark-25);
    border: 0;
    box-shadow: none;
    color: var(--color-white);
}
.range-container input.ranged {
    background-color: transparent;
}

.range-container .arrow {
    display: block;
    width: 40px;
    height: 40px;
    cursor: pointer;
    background-repeat: no-repeat;
    background-position: center;
    background-color: var(--color-bg-light-25);
}
.range-container .less {
    background-image: url('https://image.news.email.sanofi/lib/fe35117175640475751276/m/1/028c1fbe-1676-44bf-b4d1-c25b9a49f87f.png');
}
.range-container .more {
    background-image: url('https://image.news.email.sanofi/lib/fe35117175640475751276/m/1/b298a02b-64ce-4002-a47c-eb2078022c62.png');
}

.range-container .custom-number-container {
    display: flex;
    flex-direction: row;
    justify-content: center;
    align-items: center;
}

.hidden {
    display: none !important;
}

.custom-select {
    border: 1px solid #7A00E6;
    color: white;
    padding: 13px 16px;
    max-width: 300px;
    margin: 0 auto;
    position: relative;
    z-index: 10;
    cursor: pointer;
}
.custom-select .select-selected::before {
    content: '+';
    position: absolute;
    color: #7A00E6;
    top: calc(50% - 12px);
    right: 15px;
}

.custom-select.select-values {
    color: white;
    background-color: var(--color-secondary);
}
.custom-select.select-values .select-selected::before {
    color: white;
}
.custom-select .select-selected.active::before {
    color: white;
    z-index: 20;
}
.select-items {
    display: none;
    position: absolute;
    background-color: white;
    color: #7A00E6;
    width: 100%;
    left: 0;
    top: 0;
}
.select-items div {
    padding: 13px 16px;
}
.select-items div:first-child {
    background-color: #7A00E6;;
    color: white;
}
.select-items.active {
    display: block;
}

.custom-range-container {
    position: relative;
    margin: 20px auto;
    display: flex;
}

.ranged {
    width: 100%;
    -webkit-appearance: none;
    appearance: none;
    background: #d3d3d3;
    outline: none;
    -webkit-transition: .2s;
    transition: opacity .2s;
    position: relative;
    z-index: 5;
}
.ranged::-webkit-slider-thumb {
    -webkit-appearance: none;
    appearance: none;
    border-radius: 50%;
    width: 38px;
    height: 38px;
    background-color: var(--color-white);
    border: 10px solid var(--color-secondary);
    cursor: pointer;
}

.ranged::-moz-range-thumb {
    width: 38px;
    height: 38px;
    border-radius: 50%;
    background-color: var(--color-white);
    border: 10px solid var(--color-secondary);
    cursor: pointer;
}

/* Línea detrás del rango */
.range-track-bar {
    position: absolute;
    width: 100%;
    height: 8px;
    border-radius: 25px;
    background: var(--color-bg-dark-25);
    top: calc(50% - 4px);
    z-index: 0;
}
.range-track {
    position: absolute;
    width: 0;
    height: 8px;
    border-radius: 25px;
    background: var(--color-secondary);
    top: calc(50% - 4px);
    z-index: 2;
}


/* Marcas verticales */
.range-mark {
    position: absolute;
    width: 2px;
    height: 24px;
    background: var(--color-secondary);
    top: 50%;
    transform: translateY(-50%);
    opacity: 0.5;
    z-index: 0;
}

.block-three {
    display: flex;
    flex-direction: row;
    max-width: 500px;
    margin: 0 auto;
}
.block-three .three-items {
    flex: 1 1 33%;
    display: flex;
    flex-direction: column;
    align-items: center;
    text-align: center;
    justify-content: center;
    color: white;
    font-size: 12px;
}
.block-three .three-items .image {
    height: 80px;
}
.block-three .three-items img {
    width: fit-content;
}
.four-items .image a {
    position: relative;
    height: 100%;
    width: 100%;
    display: block;
}
.four-items .image a:before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    bottom: 0;
    right: 0;
    opacity: 0;
    background-color: #000;
    transition: 0.3s ease-in-out;
}
.four-items .image a:hover:before {
    opacity: 0.2;
   
}
.four-items .image a img {
    transform: scale(1);
    transition: 0.3s ease-in-out;
}
.four-items .image a:hover img {
    transform: scale(1.05);
}
.video {
    max-width: 500px;
    margin: 30px auto 0;
}
.block-four {
    display: flex;
    flex-direction: row;
    justify-content: center;
    gap: 12px;
}
.block-four .link {
    padding-top: 16px;
    text-align: center;
}
.uppercase {
    text-transform: uppercase;
}

.two-row {
    display: flex;
    flex-direction: row;
    gap: 70px;
}
.two-row .info {
    text-align: center;
    color: var(--color-white);
    width: 50%;
}
.two-row .image {
    overflow: hidden;
    width: 50%;
}
.return {
    min-width: 60px;
    height: 60px;
    display: flex;
    justify-content: center;
    align-items: center;
    background-color: var(--color-secondary);
    margin-right: 10px;
    transition: 0.3s ease-in-out;
}
.return:hover {
    color: var(--color-secondary);
    background-color: var(--color-white);
}
.return:hover path {
    fill: var(--color-secondary);
 
}
.next.btn-primary {
    width: 100%;
    height: 60px;
    display: flex;
    justify-content: center;
    align-items: center;
    background-color: var(--color-secondary);
    font-size: 18px;
    text-transform: uppercase;
    font-weight: bold;
    color: var(--color-white);
    text-decoration: none;
    transition: 0.3s ease-in-out;
}
.next.btn-primary:hover {
    color: var(--color-secondary);
    background-color: var(--color-white);
}
.next {
    width: 100%;
    height: 60px;
    display: flex;
    justify-content: center;
    align-items: center;
    background-color: var(--color-white);
    font-size: 18px;
    text-transform: uppercase;
    font-weight: bold;
    color: var(--color-secondary);
    text-decoration: none;
    transition: 0.3s ease-in-out;
}
.next:hover {
    color: var(--color-white);
    background-color: var(--color-secondary);
}
.list-icons {
    display: flex;
    flex-direction: column;
    gap: 20px;
}
.list-icons div {
    display: flex;
    flex-direction: row;
    align-items: center;
    gap: 12px;
    font-size: 16px;
    line-height: 18px;
    font-weight: bold;
}
.two-row .three-block {
    display: flex;
    flex-direction: row;
    gap: 30px;
    justify-content: center;
    align-items: start;
}
.two-row .three-block div {
    width: 100px;
    text-align: center;
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
}

.two-row .three-block .circle-primary { 
    background-color: var(--color-secondary);
    width: 80px;
    height: 80px;
    border-radius: 50%;
    display: block;
    display: flex;
    justify-content: center;
    align-items: center;
}
.two-row .three-block p { 
    font-size: 13px;
    line-height: 16px;
    font-weight: 500;
    color: white;
    text-align: center;
    margin-top: 12px;
}
.ph-16 {
    padding: 0 16px;
}
iframe {
    width: 100%;
}


.mat-es {
    writing-mode: vertical-rl;
    font-size: 10pt;
    color: var(--color-secondary);
    padding-right: 8px;
    position: absolute;
    left: 18px;
}
@media (max-width: 1124px) {
    main {
        height: 100%;
        width: 100%;
        flex-direction: column-reverse;
    }
    .mat-es {
        display: flex;
        justify-content: end;
        position: inherit;
        width: 100%;
        writing-mode: inherit;
        padding-right: 0;
        justify-content: center;
        padding-top: 30px;
        height: auto;
    }
}
footer {
    text-align: center;
    padding: 60px 0 30px;
}
footer a {
    font-size: 10pt;
    color: var(--color-secondary);
    text-decoration: none;
    transition: 0.3s ease-in-out;
}
footer a:hover {
    color: var(--color-secondary);
    text-decoration: underline;
}
.image img {
    width: 100%;
}
@media (max-width: 728px) {
  
    .container {
        padding: 0;
    }
    .block-four {
        gap: 40px;
        column-gap: 20px;
        flex-wrap: wrap;
        padding-bottom: 60px;
    }
   
    .two-row {
        flex-direction: column;
    }
   
    .two-row .info,
    .two-row .image {
        width: 100%;
    }
    .container .content {
        padding: 25px;
    }
    .range-container {
        flex-direction: column-reverse;
        gap: 12px;
    }
    .range-container .custom-number-container {
        width: 100%;
    }
    .range-container .custom-number-container input {
        width: 100%;
    }
   
    .two-row .three-block {
        gap: 0;
    }
    .two-row {
        gap: 45px;
    }
}

@media (max-height: 850px) {
    main {
        height: auto !important;
    }
    main h1 {
       font-size: 2rem;
    }
}
@media (max-width: 420px) {
    .cta-home img {
        width: 100%;
    }
}
@media (max-width: 364px) {
    .ph-16 {
    padding: 0 20px;
    }
}
  